Your assessment suggests that supporting bone integrity, calcium metabolism, and neuromuscular function may be beneficial. Here’s how Osteo+Core addresses your profile.

ZENUTRI Osteo+Core delivers a clinically relevant combination of Vitamin D3 (colecalciferol) 25mcg and Vitamin K2 (as menaquinone-7) 180mcg — two fat-soluble vitamins with complementary and synergistic roles in calcium regulation, bone mineralisation, and skeletal integrity. Formulated for adults seeking structured long-term bone maintenance, particularly those with limited sun exposure, age-related changes in bone metabolism, or elevated skeletal demand.

The Calcium Regulation Pathway — Why D3 and K2 Work Together

Bone strength is not determined by calcium intake alone. It depends on the coordinated absorption, distribution, and directed utilisation of calcium — processes that are tightly regulated by vitamins D3 and K2. Without both, supplemental calcium may not reach bone tissue effectively, and circulating calcium may accumulate in soft tissues and vascular walls rather than being directed to the skeleton.

Vitamin D3 (colecalciferol) is the biologically active form of vitamin D synthesised in the skin upon UV-B exposure. It supports intestinal absorption of dietary calcium and phosphorus, and contributes to maintaining adequate circulating calcium levels necessary for bone mineralisation, neuromuscular function, and immune modulation. Vitamin D insufficiency is highly prevalent in Australia despite adequate sun availability, particularly in adults who work indoors, wear sunscreen consistently, or have limited outdoor time during the winter months.

Vitamin K2 (as menaquinone-7) activates osteocalcin — the bone matrix protein responsible for binding calcium into bone tissue — and activates matrix Gla protein (MGP), which inhibits calcium deposition in arterial walls. The MK-7 form is selected specifically for its extended biological half-life (compared to MK-4), which supports consistent daily activation of these vitamin K-dependent proteins at the doses provided. Together, D3 and K2 form a complete calcium regulation system: absorption, transport, and directed skeletal deposition.

Targeted Clinical Benefits

Osteo+Core is formulated to support skeletal and metabolic health across six interconnected physiological targets:

• Support bone mineralisation and maintenance of normal bone density through the D3/K2 calcium regulation pathway
• Maintain bone strength and structural integrity under physical load and age-related metabolic change
• Support calcium absorption from the diet via vitamin D3-mediated intestinal transport mechanisms
• Maintain healthy neuromuscular function through adequate vitamin D status and calcium availability
• Support muscle function and physical performance via vitamin D receptor-mediated pathways
• Contribute to immune system support through vitamin D3 immunomodulatory activity

Who Osteo+Core Is Designed For